A nerve in your neck helps keep inflammation in check.
About SN111 Claims
Claims - Subnet 111@DeSciClaimsA nerve in your neck helps keep inflammation in check. A trial of 242 people has now used it to treat rheumatoid arthritis. The idea: signals travelling down the vagus nerve tell immune cells to ease off. Everyone in the trial had #RheumatoidArthritis and had tried at least 1 advanced drug that failed them or that they couldn't tolerate. All 242 had a device about 2.5 cm long implanted on the vagus nerve in the neck. In 122 of them it was switched on for 1 minute a day. In the other 120 it stayed silent. Same surgery, same device, and neither the patients nor the assessors examining their joints knew who had which. After 3 months, 35.2% of the patients with the active device had improved by at least 20% on the standard arthritis score. Among the patients with the silent device, 24.2% had. That gap is modest, and the authors say it is smaller than drug trials typically show at 3 months. It is also 1 trial, sponsored by @SetPointMed, which makes the device. After month 3 every patient was switched on, so the later results have no comparison group. And it is surgery: 4 of the 243 people enrolled had a serious surgery-related complication. All 4 resolved. The FDA approved the device in July 2025. Tesser, J. R. P. et al. Vagus nerve-mediated neuroimmune modulation for rheumatoid arthritis: a pivotal randomized controlled trial. Nat. Med. 32, 369–378 (2026). This paper went through Claims: 17 claims, each tied to its evidence.
SN111 Claims at a glance
SN111, Claims (α token Ё), is one of the independent markets on the Bittensor network, each with its own α token and its own price. Its α currently trades at 0.004362 τ (≈ $1.32), against 5,601 τ of pool liquidity. On-chain, the best-delegated validator on it yields about 36.42% APR (simple) and 43.94% APY (compounded), emissions add 0.000395 τ to the pool each block, epochs run every 360 blocks. It was registered at block #5,615,562.
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